Treatment Resistant Schizophrenia

David L. Fogelson, M.D. Clinical Professor of Psychiatry David Geffen School of Medicine at UCLA And The Semel Institute for Neuroscience and Human Behavior at UCLA Adapted from a PowerPoint Presentation created by Stephen Marder, M.D., 2018, used with permission 19 year old mute college student responding to internal stimuli She was unable to give […]

Bipolar spectrum disorder masquerading as
treatment resistant unipolar depression

By David L. Fogelson and Bruce L. Kagan EditorialCite this article: Fogelson DL, and Kagan BL (2020). Bipolar spectrum disorder masquerading as treatment resistant unipolar depression. CNS Spectrums Received: 11 October 2020Accepted: 06 November 2020 We are frequently consulted by patients with treatment resistant depression (TRD). Many of thesepatients have never met criteria for a […]

Avoidant personality disorder symptoms in first-degree relatives of schizophrenia patients predict performance on neurocognitive measures

The UCLA family study Whether avoidant personality disorder symptoms are related to neurocognitive impairments that aggregate in relatives of schizophrenics is unknown. We report the relationship between avoidant personality disorder symptoms and neurocognitive performance in the first-degree relatives of probands with schizophrenia. 367 first-degree relatives of probands with schizophrenia and 245 relatives of community controls […]

Avoidant personality disorder is a separable schizophrenia-spectrum personality disorder

Even when controlling for the presence of paranoid and schizotypal personality disorders The UCLA family study It is unresolved whether avoidant personality disorder (APD) is an independent schizophrenia (Sz)-spectrum personality disorder (PD). Some studies find APD and social anxiety symptoms (Sxs) to be separable dimensions of psychopathology in relatives (Rels) of schizophrenics while other studies […]

MMPI vulnerability indicators for schizophrenia and attention deficit disorder:

UCLA family study of biological parents of offspring with childhood-onset schizophrenia or ADHD Minnesota Multiphasic Personality Inventory (MMPI) scores were examined for 50 parents of children with an onset of schizophrenia prior to 14 years of age, 153 parents of children with attention deficit hyperactivity disorder (ADHD), and 168 parents of community comparison children. The […]